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What Is LSD 25

What Is LSD 25?

Giordano Novak

Giordano Novak

Medically reviewed by Giordano Novak, University of São Paulo on April 3rd 2022

Key Takeaways:

  • LSD 25, also known as lysergic acid diethylamide-25, is a hallucinogenic drug derived from ergot fungus.
  • LSD 25 alters perception, mood and emotion by affecting serotonin levels in the brain.
  • The acute effects of LSD are unpredictable, can vary greatly from person to person and depend heavily on environmental factors like set (user’s mindset) and setting (surroundings).
  • LSD acts on several different neural pathways, including serotonin receptors and dopamine receptors. Generally, it has subjective effects.


Nothing quite compares to an LSD high, and the experience can improve your life. While the risk of a bad acid trip is always there, the good trips are worth it. 

But before you take LSD, isn’t it a good idea to know a little bit more about what it actually is?

When LSD was discovered, it was the 25th variation of lysergamides that Albert Hoffman synthesized successfully while he was attempting to develop a new analeptic. As a result, the discovery was named LSD-25.

In this article, I will take you through everything you need to know about what LSD 25 is, how it works, and how it can benefit you. That way, you can make a more informed decision about whether this drug will be right for you.


What is LSD 25?

LSD 25 (called Lysergic Acid Diethylamide) is a powerful psychoactive drug made from ergot compounds that affect the brain’s serotonin levels and causes altered perceptions, feelings, and experiences [1].

LSD 25 works by binding to serotonin receptors in your brain, which increases serotonin levels significantly. Once this occurs, the user can experience altered perceptions, feelings and experiences that last anywhere from 6-14 hours.


Matt Smith, WebMD LSD Quote (White)


Pro Tip: Combining lysergic acid diethylamide-25 with other substances can be dangerous and even fatal, so it is important to understand how the drug works and its effects before use.


The chemical structure of LSD 25 is similar to various biologically active compounds produced in the human body, such as serotonin and melatonin.

This similarity allows for its effects to be more pronounced than many other psychedelic drugs, making it one of the strongest and most powerful hallucinogenic substances available.


Pro Tip: Acid cannot cause physical dependence, which is why it is not classed as an addictive drug. However, you can build a tolerance to it, and this can lead to drug abuse.


Effects of LSD 25

When someone takes LSD, they can experience a range of positive effects, such as increased creativity, euphoria, and intense spiritual experiences. This intense LSD experience is often referred to as “trips”.

The potential risks associated with taking LSD 25 include anxiety, paranoia, hallucinations, and disorientation. 

As the drug is so unpredictable in terms of its effects, it is important to be well-informed and aware of potential risks before taking LSD 25.


Pro Tip: LSD should never be mixed with other drugs or alcohol. It can have adverse effects on your mind and body.


Those who suffer from mental health conditions such as schizophrenia should avoid taking acid as they have an increased chance of developing HPPD (Hallucinogen Persisting Perception Disorder), a condition where the user experiences long-lasting visual disturbances [4].

LSD should never be mixed with antidepressants or SSRIs as it can cause serotonin syndrome (essentially a serotonin overdose), which can be fatal [5]. The symptoms of serotonin syndrome include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Fever
  • High blood pressure
  • Confusion and disorientation
  • Shivering and tremors


Benefits and Uses of LSD 25

LSD 25 has been used in a variety of therapeutic settings (e.g. psychotherapy) to help patients cope with mental health issues, such as depression and anxiety [2]. 

It has also been studied for its potential use in treating alcoholism, addiction, and cluster headaches [3].

LSD 25 can also be beneficial to those who are looking to explore their creativity and spirituality. 

It has been used in many contexts to help people gain new insights into themselves and the world around them and increase their sense of connection with nature.


How to Take LSD 25?

LSD 25 is usually taken orally. It can come in the form of tablets, liquid droplets, or gelatin squares (also known as “blotters”). 

The effects of LSD 25 typically begin within 30 minutes to an hour after taking it, and they usually last between 6-14 hours.

It is important to note that LSD 25 is a powerful hallucinogenic drug. As such, it should not be taken lightly, and it should only be taken under the supervision of an experienced professional or in a safe environment.


Pro Tip: While the concept of psychedelic medicine is becoming quite popular, an LSD trip does not count as such. More research on its effects is needed.


Best Place to Buy LSD 25 Online in Canada

If you want to buy LSD, going online is definitely an option. However, you need to be careful who you buy your supply from. 

This is because some dealers have been known to lace their supply with filler ingredients and chemicals, which could be harmful to your health.

The reason for this is that it leads to lower costs for them and more profit. This is why we are always careful who we recommend, and we only link you to trusted sellers that have a great reputation and will provide you with pure acid. We want you to be safe.


To Conclude

LSD 25 is a powerful psychoactive drug that can cause altered perceptions, feelings, and experiences. It has been used in various therapeutic settings to help treat mental health issues, addiction, and cluster headaches.

What’s more, it can be beneficial for those looking to explore their creativity and spirituality. 

Due to its unpredictable effects, lysergic acid combinations with other substances should be avoided at all costs, as the reacting lysergic acid could have deadly results.

Finally, if you are considering using LSD 25, do your research and be aware of the potential risks to make an informed decision about whether this drug is right for you.



1: Liechti ME. Modern Clinical Research on LSD. Neuropsychopharmacology. 2017;42(11):2114-2127. doi:10.1038/npp.2017.86

‌2: Fuentes JJ, Fonseca F, Elices M, Farré M, Torrens M. Therapeutic Use of LSD in Psychiatry: A Systematic Review of Randomized-Controlled Clinical Trials. Frontiers in Psychiatry. 2020;10. doi:10.3389/fpsyt.2019.00943

‌3: Krebs T, Johansen P. Lysergic acid diethylamide (LSD) for alcoholism: meta-analysis of randomized controlled trials. Published 2013. Accessed January 7, 2023.

‌4: Hermle L, Simon M, Ruchsow M, Geppert M. Hallucinogen-persisting perception disorder. Therapeutic Advances in Psychopharmacology. 2012;2(5):199-205. doi:10.1177/2045125312451270

‌5: Singh A, Puskoor S, Saunders R. PROLONGED LYSERGIC ACID DIETHYLMIDE INDUCED SEROTONIN SYNDROME. Chest. 2019;156(4):A2132. doi:10.1016/j.chest.2019.08.2076

6: Hallucinogens: Future of Mental Health Treatment? (2017, January 13). WebMD. Available at:


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