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Building a Tolerance Of LSD

Building a Tolerance Of LSD

Giordano Novak

Giordano Novak

Medically reviewed by Giordano Novak, University of São Paulo on April 3rd 2022

Key Takeaways:

  • LSD tolerance varies from person to person and is influenced by factors such as body weight and metabolism.
  • LSD can have a cross-tolerance with other psychedelics, meaning that an individual’s tolerance for LSD may be higher if they have previously taken similar drugs.
  • Establishing a baseline dose of LSD before increasing it is essential to ensure safety while learning how much LSD your body can handle.
  • Start low and go slow when dosing LSD; increase your dosage slowly over time until you discover what amount works best for you.


Taking LSD can be a welcome escape from the world and a great way to relax when you’re feeling stressed and overwhelmed. 

We’d never advocate using acid every day, even if it isn’t an addictive drug, mostly because drug abuse can become a problem, and you might build up a tolerance.

It is possible to build a tolerance to LSD, especially if you take it frequently. This can lead to an increased risk of drug abuse, especially if you keep upping the dose to match your tolerance, and many LSD users stick with microdosing to avoid this.

In this guide, I’ll take you through everything you need to know about how LSD tolerance works so that you can stay safe while enjoying the high. Even with a relatively safe drug like acid, dosing is still important.


What Is LSD?

LSD, also known as lysergic acid diethylamide, is a PSYCHEDELIC drug derived from ergot fungus that grows on rye. LSD has been used for recreational purposes since the 1960s and is still POPULAR today.

It produces notable CHANGES in perception, mood, thought, and behavior, as well as altered states of consciousness. 

Other things you might notice during an LSD high are hallucinations, increased energy levels, and ENHANCED sensory perception [2].

Can You Build a Tolerance to LSD?

LSD is not an addictive drug, but users can build a TOLERANCE when they take it frequently. Clinical implications are that they NEED to increase the dose to get the same effects as before [1].

Surprisingly, LSD has one of the lowest tolerance levels of any psychedelic – some people build up a tolerance in a SINGLE session.

Acid can ALSO have a cross-tolerance with other psychedelics, meaning that an individual’s tolerance for LSD can be higher if they have previously taken drugs like psilocybin mushrooms or mescaline.


Pro Tip: LSD does not cause physical dependence (no physical withdrawal symptoms) and so is not classed as an addictive drug. It’s tolerance that can lead to drug abuse.


What Is LSD Tolerance Calculator?

An LSD tolerance calculator is a tool to help you determine the OPTIMUM dose for LSD based on your body weight and recent LSD use. 

The calculator considers any existing tolerance you may have developed and any OTHER drugs you are taking.

With this information, the LSD tolerance calculator will provide an ACCURATE estimate of what dose is safe for you to take.

An example of an LSD tolerance calculation is as follows:

  • Body Weight: 160lbs
  • Average LSD Dose Taken (last 12 months): 1 tab
  • Current LSD Tolerance Level: Low
  • Recommended LSD Dosage: 0.25-0.5 tabs


Alcohol and Drug Foundation LSD Quote (White)

What Happens if You Take Too Much Acid Long-Term?

If you take LSD too frequently and develop a tolerance, there is an increased RISK of abuse. 

Taking acid in higher doses (chronic LSD use) can lead to SERIOUS health risks such as paranoia, depression, anxiety, confusion, panic attacks, hallucinations, and psychosis.


Pro Tip: When tolerance develops, the psychedelic effects of LSD become less – especially for those with chronic intoxication on the drug.


Those who have existing mental health conditions such as schizophrenia are at a HIGHER risk of developing hallucinations or drug-induced psychosis from LSD, so be sure to speak with your doctor BEFORE taking acid.

There is also a risk of HPPD (Hallucinogen Persisting Perception Disorder), which is a condition where LSD flashbacks occur frequently, and the user will experience audio or visual hallucinations [3]. 

This can last anywhere from a day to several YEARS.

How Long Does it Take to Reset Your Acid Tolerance?

When it comes to acid, tolerance is dose-dependent. As a general rule of thumb, LSD tolerance will return to NORMAL levels within one day of recovering from LSD’s effects.

Repeated LSD treatment will lead to reduced behavioral tolerance, and while there is no LSD withdrawal, the possibility of PSYCHOLOGICAL dependence remains.

However, LSD can have a cross-tolerance with other psychedelics such as psilocybin mushrooms and mescaline, so if you’ve been using MULTIPLE drugs, then it can take up to a week for your LSD tolerance to reset.

Is it Safe to Take More LSD When My Tolerance Increases?

It is not advisable to take LSD more frequently or in larger doses as your tolerance increases. LSD tolerance can build quickly, so it’s IMPORTANT to stick with the same dose each time and only INCREASE if absolutely necessary.

There is NO lethal dose of acid, and you cannot have complete tolerance to the drug. However, your initial dose should still be SMALL so that you can get used to the effects.

Microdosing LSD is one way to avoid building up a tolerance, as this involves taking very LOW doses of LSD on a regular basis. This can help to reduce the risk of LSD abuse and HPPD while still providing some of LSD’s benefits, such as improved creativity, focus, and mood.


Pro Tip: If you do increase your dose, always remember to start low and go slow – this will help you to stay safe and enjoy LSD’s benefits without the risks associated with LSD abuse.


Best Place to Buy LSD Online in Canada

Buying LSD online is pretty easy, but you have to watch who you buy from. We only ever recommend highly TRUSTED and reputable sellers, people we have worked with to ensure you’re getting a safe and pure product. 

But do you really NEED to worry about the purity of acid?

Watering down LSD and using filler ingredients to bulk it up is a common practice among dodgy dealers who are looking to MAXIMIZE their profits. 

It can be harmful to your health and even lead to poisoning. If you’re planning on trying acid, we want you to be SAFE while doing so.

That’s why you should check out our trusted vendor and see what they have to offer.


To Conclude

Acid has been used recreationally since the 1960s and is still popular today. It produces notable CHANGES in perception, mood, thought, and behavior, as well as altered states of consciousness.

LSD users can develop a tolerance over time if they take it FREQUENTLY and need to increase their dose to get the same effects.

An LSD tolerance calculator can help acid users determine the appropriate dose based on their body weight and LSD history. It’s important to start low and go SLOW when increasing the dose, and always buy LSD from a trusted vendor to ensure you are getting a safe, pure product.


1: Buchborn T, Grecksch G, Dieterich DC, Höllt V. Tolerance to Lysergic Acid Diethylamide. Neuropathology of Drug Addictions and Substance Misuse. Published online 2016:846-858. doi:10.1016/b978-0-12-800212-4.00079-0

‌2: Liechti ME. National Institute. Modern Clinical Research on LSD. Neuropsychopharmacology. 2017;42(11):2114-2127. doi:10.1038/npp.2017.86

‌3: Hermle L, Simon M, Ruchsow M, Geppert M. Hallucinogen-persisting perception disorder. Therapeutic Advances in Psychopharmacology. 2012;2(5):199-205. doi:10.1177/2045125312451270

4: LSD as a therapeutic treatment – Alcohol and Drug Foundation. (n.d.). Available at:



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