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LSD vs Shrooms: What Is The Difference

LSD vs Shrooms: What Is The Difference

Giordano Novak

Giordano Novak

Medically reviewed by Giordano Novak, University of São Paulo on April 3rd 2022

Key Takeaways:

  • LSD and Shrooms are two different types of psychedelics that can induce altered states of consciousness.
  • While both LSD and shrooms have similar effects, they differ in their duration, potency, and other factors.
  • LSD is usually more potent than shrooms, has a longer duration of action, and can be much more intense in its effects.


Are you curious about the differences between LSD and shrooms? I know I am. It can be difficult to tell them apart with their respective reputations of being both psychedelic substances. But don’t worry – that’s what I’m here for!

Well, LSD is made from lysergic acid, while shrooms are a natural fungus containing psilocybin and other compounds. The effects of these two drugs also differ, with LSD producing more vivid visuals and mental stimulation than shrooms.

In this article, we will explore the major similarities and differences between these two substances so you can decide which one is right for you. So buckle up, my friends – let’s take a trip down trippy lane.


LSD vs Shrooms – What Are They?

LSD (Aka Acid)

Being able to take an LSD trip (or, as the cool kids call it – acid) has been an ADVENTURE since the 60s, although first synthesized in 1938 [1]. It’s an opportunity to delve into your own brain and explore the inner depths of your mind in ways you’ve never experienced before.

LSD (Lysergic Acid Diethylamide) is a psychedelic drug that often produces hallucinogenic effects – including the feeling of flying, INTENSE changes in visual perception, synaesthesia and more.

While being on “the trip” can be an OVERWHELMING experience at times, it also comes with many positives – like gaining fresh perspectives and seeing your everyday life in an entirely new light.

Pro Tip: If you’re looking for a more intense or spiritual experience, then LSD is the way to go.


Nancy A. Melville LSD Quote (White)


Magic Mushrooms (aka Shrooms)

Let me tell you a bit about them from someone who’s researched way more on ‘magic mushrooms’ (aka shrooms) than I ever planned to. They are fungi that CONTAIN psychoactive compounds, or in simpler words, they make you trip!

You can take psilocybin mushrooms in a few DIFFERENT ways – dried and eaten raw, cooked, brewed into tea or added to food like pizzas and brownies. It’s not just recent; they have been around since the prehistoric era – people just loved how their effects made them feel [2].

I’m sure you’ve seen pictures of characters running around trying to catch shrooms – now you know why. All jokes aside, make sure you know what you’re doing BEFORE experimenting with psychedelic mushrooms.


LSD vs Shrooms: What’s the Difference?

When it comes to psychedelics, the debate between LSD and mushrooms is one for the ages! On a FACTUAL level, though, it’s clear that there are sizeable differences.

The biggest one? LSD is synthesized in a lab, while mushrooms grow NATURALLY within our outdoor environment. Coming from two very distinct sources, it’s no surprise that they each offer unique experiences.

Some might prefer the carefully CRAFTED version of letting loose found in an LSD trip, while others opt instead for the wilder ride of natural mushrooms. Whatever your preference, there’s no doubt you can find something groovy to suit your needs!


Side Effects:

While they may look and taste different, shrooms and LSD actually have a lot in COMMON … well, at least when it comes to the psychedelic effects! Let’s take a closer look:

  • Vivid visual and mental stimulation
  • Distorted perception of space and the time
  • Enhanced senses and spiritual experiences
  • Altered sense of smell, taste and touch
  • The feeling an object is moving or melting
  • Excitement
  • Nausea
  • Anxiety
  • Increased heart rate
  • Fear of death
  • Dilated pupils
  • High blood pressure
  • Sweating
  • Tremors



It’s IMPORTANT to remember that the effects of LSD and shrooms vary wildly depending on factors like dosage, tolerance, method of administration and other substances taken.

The RECOMMENDED dosage for an average user is between 50-100 micrograms (μg) for LSD [3], while a moderate dose of shrooms can range anywhere from 2-5 grams.

Of course, it’s always SMART to start with a low dose and build up over time as you get more used to the effects. The key is finding the perfect balance for your body and mind.


Method of use:

LSD is most COMMONLY taken orally or, less often, nasally. It’s usually found in liquid form and on blotter paper, sugar cubes and gelatin squares.

On the other hand, magic mushrooms are usually eaten raw or brewed into tea. Dried mushrooms can also be ADDED to food such as pizza or brownies.

No matter which method you choose, make sure to take your time and respect the power of these substances.


Pro Tip: It’s always a good idea to have a ‘psychonaut buddy’ with you when experimenting with psychedelics.


The High:

LSD is more commonly known to produce a VIBRANT mental trip lasting up to 12 hours. While the mushroom trip typically lasts between 4-6 hours.

Both mushroom and LSD trips may cause mild to intense auditory and visual hallucinations, INCREASED energy levels, altered perception of time and space, and powerful spiritual experiences.

The Dangers:

Ultimately, consuming any amount of psychedelic drugs comes with some RISK. It’s important to be aware of the risks and take necessary precautions before trying either one.

The most common dangers associated with both LSD and shrooms include:

  • Anxiety or panic attacks
  • Paranoia
  • Adverse reactions from mixing psychedelics with other drugs or alcohol
  • Increased heart rate & blood pressure
  • Dehydration
  • Poor judgement
  • Flashbacks
  • Poor mental health
  • Drug abuse
  • Withdrawal symptoms
  • Overdose

The side effects are MORE concerning for people who suffer from any heart or mental health condition [4]. It’s also important to remember that psychedelics can increase the risk of psychological distress if you’re feeling overwhelmed or overwhelmed by the experience.


Are Shrooms or Acid For Me?

At the end of the day, it’s important to do your RESEARCH and think carefully about which psychedelic experience is right for you. Consider factors like dosage, method of use, potential risks, and how you want to feel before taking any psychedelics.

If you decide that shrooms or LSD are right for you, remember to take the time to find a SAFE and comfortable setting, avoid mixing with other substances, and trust your own judgement.


What About Mixing Mushrooms and LSD?

Mixing these two psychedelics can be DANGEROUS and is not recommended. Not only could it increase the risk of a bad LSD trip, but mixing them together can also cause unpredictable reactions that could potentially lead to serious physical or psychological harm.

It’s best to stick with EITHER one – and if you’re feeling particularly brave, you can try gradually increasing your dosage over time.



Psychedelics, such as LSD and mushrooms, can offer powerful experiences that may lead to spiritual growth and potential therapeutic benefits.

However, it’s important to proceed with caution when using these substances – be sure to do your research beforehand and take necessary precautions before embarking on a psychedelic journey.

Remember to start slowly with a low dose, find a safe setting for the experience, and avoid mixing psychedelics. With proper knowledge about the effects of psychedelics like shrooms or acid, you can decide whether they are right for you!



  1. Editors. LSD. HISTORY. Published June 14, 2017. Accessed December 21, 2022.
  2. Best Ways To Take Shrooms (Psilocybin) – Spinfuel. Spinfuel. Published February 28, 2022. Accessed December 21, 2022.
  3. Holze F, Vizeli P, Ley L, et al. Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects. Neuropsychopharmacology. 2020;46(3):537-544. doi:10.1038/s41386-020-00883-6
  4. Robitzski D. LSD and Shrooms Linked to Lower Heart Disease and Diabetes Risk. Futurism. Published October 13, 2021. Accessed December 21, 2022.

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