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Medically reviewed by Giordano Novak, University of São Paulo on April 3rd 2022
Wait, isn’t it just plain LSD? While LSD has been a mainstream psychedelic drug for quite some time, it’s not the only form on the market.
Those who are a little savvier might have heard of 1p LSD, but this isn’t the case for everyone. So, what is it?
1p LSD is an analog of LSD. 1p is often used as a substitute due to its similar effects and chemical structure.
The full effects of 1p are unknown as there have not been enough clinical studies to determine how different it is from standard acid.
In this article, we will take you through everything we know about 1p LSD and the way it works. That way, you’ll have a clearer idea of what to expect if you ever decide to try it.
1-propionyl-lysergic acid diethylamide (1P-LSD) is a semi-synthetic psychedelic substance of the lysergamide class. 1P-LSD is thought to produce its psychedelic effects by ACTING on serotonin receptors in the brain [1].
1P-LSD belongs to a group of related compounds known as lysergamides, which includes other well-known psychedelics like LSD and 1A-LSD. It can be taken as a human serum with intravenous or oral ingestion.
It is considered one of several NEW psychoactive substances since its creation in 2015. While it is not listed as one of the psychoactive substances prohibited by LAW in Canada, caution should still be taken.
1P-LSD is similar to LSD, with the main difference being that 1P-LSD has a propionyl group bound to the 1 position of its indole ring.
This modification appears to slightly increase 1P-LSD’s affinity for serotonin receptors in comparison to REGULAR acid and may account for some subtle differences in the subjective effects.
1P-LSD is also thought to be slightly more potent than LSD, with less of it needing to be taken in order to experience its full range of effects.
No, 1p LSD is not thought to be addictive as it does not activate the brain’s reward system in the same way as some OTHER psychoactive drugs do.
However, 1p-LSD can still produce compulsive and REPETITIVE use patterns that may indicate a psychological addiction.
Those who are prone to drug and alcohol abuse should not try 1p or standard acid as it could lead to DANGEROUS habits and the mixing of drugs.
Pro Tip: LSD is found under the Psychoactive Substances Act and remains a controlled substance. While 1p might be legal, it is still listed on the new synthetic drugs database, and there are restrictions.
No, 1p LSD does not show up in standard drug testing as it is not specifically tested for. However, 1P-LSD can be detected using more ADVANCED methods such as liquid chromatography-mass spectrometry (LC-MS).
One of the main benefits of 1P-LSD is its availability. 1P-LSD is much easier to acquire than regular acid, as it can be purchased legally in some countries, including Canada.
1P-LSD also has a lower rate of tolerance build-up than regular acid, which means that users don’t need to take increasingly larger doses to feel the SAME effects [2]. This makes 1P-LSD an ideal candidate for microdosing, as users don’t need to worry about needing higher doses later on.
Finally, 1P-LSD has a more subtle set of effects than regular acid, which may make it more suitable for some users who DON’T want to be overwhelmed by intense visuals and emotions.
A 1p LSD microdose is a very small amount of 1P-LSD taken with the intention of producing subtle changes in mood, cognition, and perception [3].
Microdosing 1P-LSD is not intended to produce psychedelic effects but rather a subtle shift that can enhance creativity, productivity, and mental clarity.
Pro Tip: 1p LSD microdoses are typically taken 1-3 times a week, with users reporting that the effects can last for 1-2 days after each dose.
If you’re looking for 1p LSD Canada, it is important to remember that it is a controlled drug.
Therefore, you might have a hard time finding 1p LSD for sale – even though it is technically legal to buy. When you do buy it, just like acid, you need to ensure you go to a reputable source.
Since 1p is a designer drug, it does have chemical and structural differences from LSD.
This can make it easier to lace with POTENTIALLY harmful substances, compromising the purity of the product. Our chosen seller is trusted and reliable with an excellent reputation.
This means you get a pure product with NO risk of tampering, all for an excellent price that guarantees you get what you pay for.
1P-LSD is a semi-synthetic psychedelic substance and a derivative of lysergic acid diethylamide (LSD). 1P-LSD has effects that are reported to be similar to LSD but slightly more subtle.
1P-LSD is legal in some countries, including Canada, which makes it easier to acquire than regular acid.
1P-LSD is also well-suited for microdosing, as it appears to have a LOWER rate of tolerance build-up and its effects are more subtle in comparison to LSD.
When buying 1p, make sure you purchase from a reputable source that offers pure 1p LSD with no risk of tampering.
1: Grumann C, Henkel K, Brandt SD, Stratford A, Passie T, Auwärter V. Pharmacokinetics and subjective effects of 1P‐LSD in humans after oral and intravenous administration. Drug Testing and Analysis. 2020;12(8):1144-1153. doi:10.1002/dta.2821
2: Coney LD, Maier LJ, Ferris JA, Winstock AR, Barratt MJ. Genie in a blotter: A comparative study of LSD and LSD analogues’ effects and user profile. Human Psychopharmacology: Clinical and Experimental. 2017;32(3):e2599. doi:10.1002/hup.2599
3: Third Wave. Third Wave. Published July 15, 2020. Accessed December 31, 2022. https://thethirdwave.co/microdosing/1p-lsd/
4: Adman, A. (2022b, June 9). 50 Spectacular Psychedelic Quotes From Celebrity Psychonauts. Medium. Available at: https://medium.com/mind-medicine/50-spectacular-psychedelic-quotes-from-celebrity-psychonauts-838ac2a2f6ae
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